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KMID : 0613820070170101330
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Journal of Life Science
2007 Volume.17 No. 10 p.1330 ~ p.1335
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Antioxidative Activity of Extracts of Aged Black Garlic on Oxidation of Human Low Density Lipoprotein
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Yang Seung-taek
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Abstract
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This study was developed to assess the antioxidative activity of aged black garlic extract on lipid peroxidation and low density lipoprotein (LDL). Antioxidative activity of aged black garlic extract on human low density lipoprotein (LDL) was investigated by monitoring a barbituric acid reactive substance (TBARS). Electron donating ability (EDA) of aged black garlic, ethanol extract was higher than that alliin and water extract. Aged black garlic water and ethanol extracts inhibited the Cu2+ mediated oxidation of human LDL in a dose dependent manner at concentration of 10 and 20 μg/ml. Ethanol extract and water extract of aged black garlic almost completely inhibited J774 mediated LDL oxidation in electrophoretic mobility and conjugated diene. These results indicate that aged black garlic might play a protective antioxidant effects on LDL, probably affecting the structural properties for the LDL oxidation.
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KEYWORD
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Aged black garlic, low density lipoprotein (LDL), antioxidant
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